|Birth date:||March 16 (Pisces)|
|Emblem Frame:||Papillon Chaser (RA-006)|
|Theme Song:||Fureru Nara Sotto|
- "I said that I had taken a liking to you, had I not?"
- — Natsume Izayoi —
Natsume Izayoi (ナツメ・イザヨイ?) is the sixth female member of the Rune Angel Troupe and she pilots Papillon Chaser. She was the duchess of the Seldor Alliance unaffiliated Arms Alliance, and believed that both Seldor and EDEN were incarnations of evil. She went into her first battle, which was against the Luxiole, to show her justice. This only led to her being captured. It was soon clear that she held no real power in the Arms Alliance, but rather that the Three Marquis did. After seeing the various wrongs committed by the Three Marquis, as well as the fact that they abandoned her, she came to realize that the Seldor Alliance was not evil, and temporarily joined the Rune Angel Troupe. Her first battle as a Rune Angel Troupe member was the battle to retake Seldor from the Arms Alliance.
- In the post-game omake of Eigou Kaiki no Toki, Natsume reveals that she has 4 younger siblings.
- Natsume is voiced by Atsuko Enomoto.
- Natsume's name comes from the Japanese name for the Jujube fruit, a fruit which is used in the production of some confectioneries.